In the not so distant future, mankind has advanced to a state where complete body transplants from flesh to machine is possible. This allows for great increases in both physical and cybernetic prowess...

The series continues the relationship between two aspiring classical musicians, Megumi "Nodame" Noda and Shinichi Chiaki, as students and after graduation.

Having been given the opportunity to study in Paris, Noda accompanies Chiaki to Europe as he strives to become the accomplished conductor he always dreamt to be. (Source: Anime News Network)